Long-term accumulation of pesticides in the environment to human and animal health. Acetylcholinesterase (AChE) biosensors with highly sensitive potentiometer transducers based on the membranes of Ag, reduced graphene oxide (rGO), and chitosan (CS) has been successfully developed. The membrane was made with a composition of 0.5 mM AgNO3, 2.5 mg/mL rGO, and 2% (w/v) CS coated on the surface of the Au electrode. The composition of the membrane with three ratios, namely 1:1:2, 2:1:3, and 3:1:4. Th...

The dyes of the textile dyeing industry wastewater are harmful to humans and the environment. They should be treated before discharging into the environment. The adsorption using the spherical activated carbon can be effective to reduce the dyes. The spherical activated carbon of 3-7 µm in diameter was successfully prepared from the waste bagasse liquid using the hydrothermal method. The activation of this carbon was carried out using the KOH solution. The optimum pH and contact time were achie...

Secondary metabolites isolated from Cryptocarya was known to have various activity especially their cytotoxicity in P388 cell. There were two species of Cryptocarya studied in this research that were Cryptocarya konishii and Cryptocarya lucida. In both species, 8 isolate compounds had bioactivity as anticancer in P388 cells. This study aimed to know the binding affinity and ADMET properties of each isolated compound through P-glycoprotein substrate since this protein was reported to be responsib...

Endophytic fungi isolated from medicinal plants have high diversity and the secondary metabolites produced have biological activity. Endophytic fungi isolated from medicinal plants have been the subject of many studies on their diversity and biological activity, one of which is jambu mawar (Syzygium jambos (L.) Alston). S. jambos has long been used as a traditional medicine to treat infections caused by pathogenic bacteria in many parts of the world, including South Sumatra. This study purposed ...

There are two species of plant that grow flourishing all around Indonesia including in Banten and West Java which are Merremia vitifolia and Bidens pilosa. In this study we evaluate how these plants could be potentially used as natural preserver of fish product especially Auxis thazard, to inhibit the histamine formation, and to find out how this activity correlates to the substances in polar extract of B. pilosa flowers and M. vitifolia leaves. Liquid chromatography with tandem mass spectrometr...

Adsorption kinetics is part of adsorption and discusses the adsorption rate of an adsorbent on the adsorbate. Adsorption kinetics has an equation to determine the rate constant of adsorption, namely the pseudo-first order and pseudo-second order. In this study, methylene blue was adsorbed using a C-4-hydroxy-3-methoxyphenylcalix[4]resorcinarene (CHMFKR) adsorbent. The aim of this study to determine the effect of process parameters (concentration, pH, and processing time) on the process adsorptio...

Cadmium is a heavy metal pollutant sourced from various industries and toxic to the kidneys. Cadmium exposure can be used natural chelator of ethanol extract of the fruiting body of Ganoderma lucidum. The aim of the study was to determine the effect and effective dose of the ethanolic extract of the fruiting body of G. lucidum on reducing the toxicity effect of cadmium in male albino rats (Rattus norvegicus) Wistar strain. The research design was experimental research, which consisted of 5 treat...

Defects in graphene alter its structure, electrical characteristics, and interaction with K+ ions. The related characteristics of divacancy defect graphene and N, S codoped divacancy graphene were effectively explored using the DFTB technique. Divacancy is essential for the band gap opening. The dopants considerably enhance the density of state (DOS) intensity and alter the graphene-character bands. The depletion of density caused by the dopant is seen on the charge density isosurface. Because ...

A lithium-ion battery with PVDF-PEO synthetic polymer sheet added by LiTFSI electrolyte salt has been made by assembling method. This study aims to determine the effect of LiTFSI salt concentration on the performance of lithium-ion batteries. The composition of LiTFSI electrolyte salts was varied into 5%; 10%; 15%; and 20%. Several characterizations were carried out to determine battery performance, including Electrochemical Impedance Spectrometry (ElS), Cyclic Voltammetry (CV), Charge/Discharge...

Alpinia monopleura is an endemic plant which widespread and abundant in Sulawesi. Nevertheless, previous studies have not studied the chemical compound and biological activity. This study describes the chemical compounds and antibacterial and antioxidant properties of the essential oils isolated from A. monopleura. The essential oil was obtained by the hydro distillation method and interpreted by GCMS. Antibacterial properties were determined by the agar diffusion method, while DPPH and ABTS det...

In this study, the molecularly imprinted polymer solid-phase extraction (MISPE) method for the determination of dinitro-ortho-cresol (DNOC) before HPLC (High-performance liquid chromatography) analysis was conducted. This study aims to analyze the sorption behavior and the potential use of molecularly imprinted polymers (MIP) for DNOC extraction. MIP was prepared using a combination of methacrylic acid as the functional monomer; ethylene glycol dimethacrylate as the crosslinker, benzoyl peroxide...

This report presented the synthesis of Arumanis mango (Mangifera indica L.) leaf extract with chitosan tripolyphosphate matrix and its antibacterial activity. This research aimed to obtain an ointment formulation from mango leaf extract with chitosan tripolyphosphate matrix, to figure out the characteristics, including the particle morphology, and to determine the optimum formulation and the characterization of the antibacterial ointment. The research showed that extract morphology with chitosan...

The composite of Graphite/PbTiO3 has been synthesized for photocatalyst and photo-electrocatalyst of Methyl Orange (MO) and Methyl Violet (MV) degradation using a visible light source. The aims of the research were to study the influence of pH of the solution, iradiation time and kinetics study of MO and MV photodegradation, voltage of photoelectrodegradation of MO and MV. Composite of Graphite/PbTiO3 was synthesized by the sol-gel process with Titanium Tetraisopropoxide (TTIP) solution and Pb(N...

The ionophore has been successfully synthesized from p-t-butyl(carboxymethoxy)calix[4]arene subtituted amide. The ionophore was obtained in two steps of the synthesis reaction. The first step is the chlorination reaction of p-t-butyl(carboxymethoxy)calix[4]arene with thionyl chloride in dry benzene solvent. The product of the chlorination reaction is p-t-butyl(chloroacetylmethoxy)calix[4]arene in the form of the light brown viscous liquid with the rendemen of 78.25% and TLC (SiO2, CH3OH : CH2Cl2...

Urease has been utilized in the field of health and industry. Urease is commonly used in the form of free enzyme, so that the utilization is limited. Urease efficiency can be improved using immobilization enzyme. This research aimed to do the urease isolation, immobilization, and characterization from the winged bean seeds. This research was started by determining the amino-acid content of winged bean seeds using the Liquid chromatography-mass spectrometry (LCMS). The winged bean seeds were germ...

This study aims to examine the potential of p-tert-butylkalix[4]arene derivatives, namely 5,11,17,23-tetra-tert-butyl-25,26,27,28-tetrahydroxy-calix[4]arene (TBCA), and 5,11,17,23-tetra-tert-butyl-25-monohydroxy-26,27,28-tribenzoyloxycalix[4]arene (TBMTCA) as adsorbent for metal cations, such as Pb(II) and Fe(III). The synthesized compounds were characterized using FT-IR and 1H-NMR spectroscopy. The adsorption studies were then carried out with contact time as a parameter, while the kinetics wer...

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the virus that causes Coronavirus 2019 (COVID-19). To date, there has been no proven effective drug for the treatment or prevention of COVID-19. A study on developing inhibitors for this virus is carried out using molecular docking simulation methods. 3CL-Pro, PL-Pro, Helicase, N, E, and M protein were used as protein targets. Autodock Vina, Autodock 4.2, and PSOVina were used in this study. This study aims to obtain a model of liga...